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DeCS
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Descriptor English:
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Immunoreceptor Tyrosine-Based Inhibition Motif
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Descriptor Spanish:
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Motivo de Inhibición del Inmunorreceptor Basado en Tirosina
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Descriptor Portuguese:
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Motivo de Inibição do Imunorreceptor Baseado em Tirosina
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Synonyms English:
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Immune Receptor Tyrosine-Based Inhibition Motif
Immuno-Receptor Tyrosine-Based Inhibition Motif
Immune Receptor Tyrosine Based Inhibition Motif
Immuno Receptor Tyrosine Based Inhibition Motif
Immunoreceptor Tyrosine Based Inhibition Motif
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Tree Number:
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G02.111.570.820.709.275.500.480
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Definition English:
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A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs. |
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History Note English:
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2013
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Allowable Qualifiers English:
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Record Number:
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55099
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Unique Identifier:
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D061626
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Occurrence in VHL:
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Similar:
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DeCS CID-10 LILACS
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